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Uterine Fibroids

Uterine fibroids, also known as leiomyomas or myomas, are non-cancerous tumours that grow within or around the uterus (womb). These growths are made up of smooth muscle and connective tissue and can vary widely in size—from tiny seedlings to large masses that can distort the shape of the uterus.

Fibroids are very common, especially in women between the ages of 30 and 50. Many people with fibroids are unaware of them because symptoms are often mild. Regular check-ups help monitor any changes in menstrual flow, pressure sensations, urinary habits, or reproductive health.

Fibroids can grow as a single growth or as multiple growths. Although benign, they can have a significant impact on a person’s quality of life depending on their size, number, and location within the uterus.

Symptoms and Causes

What are the symptoms of uterine fibroids?

  • Changes in menstrual flow, such as heavier or prolonged periods
  • Occasional bleeding between cycles
  • Pelvic pressure or discomfort
  • Altered urinary patterns
  • Changes in bowel habits, including constipation
  • Discomfort during intimacy
  • Back or leg pressure
  • Abdominal bloating or fullness
  • General reproductive health concerns

The type and severity of symptoms often depend on the size, location, and number of fibroids.

What causes Uterine fibroids?

The exact cause of fibroids is unknown, but several factors are believed to influence their development:

Hormones

Oestrogen and progesterone—hormones that regulate the menstrual cycle—stimulate the growth of fibroids. This is why fibroids often shrink after menopause, when hormone levels drop.

Genetics

A family history of fibroids increases the risk of developing them.

Growth factors

Substances that help the body maintain tissues, such as insulin-like growth factor, may affect fibroid growth.

Extracellular matrix (ECM):

This material helps cells stick together. Fibroids often contain more ECM than normal uterine muscle cells, which makes them firmer.

Diagnosis and Tests

How are uterine fibroids diagnosed?

Fibroids are often found during a routine pelvic examination. If your doctor suspects fibroids, they may recommend imaging tests to confirm the diagnosis and determine the size and location of the growths.

Common diagnostic methods include:

  • Ultrasound: A pelvic ultrasound (transabdominal or transvaginal) is usually the first step in visualising fibroids.
  • Hysterosonography (saline infusion sonography): A saline solution is introduced into the uterus via a catheter during ultrasound to better visualise the uterine lining and submucosal fibroids.
  • Hysteroscopy: A thin, lighted tube (hysteroscope) is inserted through the vagina and cervix to examine the inside of the uterus.
  • Laparoscopy: A minimally invasive surgical procedure using a camera inserted through a small incision in the abdomen to view the outer surface of the uterus.

Blood tests may also be done to check for anaemia due to excessive bleeding.

Management and Treatment

How are uterine fibroids treated?

Treatment depends on the severity of symptoms, size and location of fibroids, the individual’s age, and whether they wish to become pregnant in the future. If fibroids are not causing symptoms, treatment may not be necessary.

Non-surgical treatments include:

Medications

  • Hormonal therapies: Such as birth control pills, hormonal IUDs (e.g. LNG-IUS), or GnRH agonists to reduce bleeding and shrink fibroids.
  • Tranexamic acid: Non-hormonal medication taken during periods to reduce heavy bleeding.
  • NSAIDs: Like ibuprofen or naproxen for pain relief.
  • GnRH antagonists: Newer medications that shrink fibroids by lowering oestrogen and progesterone levels without the same menopausal side effects as older treatments.

Minimally invasive procedures include:

  • Uterine artery embolisation (UAE): A radiologist injects tiny particles into the uterine arteries to block blood flow to fibroids, causing them to shrink.

Surgical treatments include:

  • Myomectomy: Surgical removal of fibroids while preserving the uterus. It may be done through the abdomen, vagina, or via laparoscopy, depending on fibroid location.
  • Hysterectomy: Complete removal of the uterus. This is the only definitive cure for fibroids and is usually reserved for women who no longer wish to conceive and have severe symptoms.
  • Endometrial ablation: A procedure that destroys the uterine lining to reduce bleeding. Not suitable for women who want to become pregnant.

Prevention

There’s no sure way to prevent fibroids, but certain lifestyle choices may help reduce your risk:

  • Maintain a healthy weight
  • Eat a balanced diet rich in fruits and vegetables
  • Limit consumption of red meat and alcohol
  • Ensure adequate levels of vitamin D
  • Manage stress and maintain regular physical activity

Regular gynaecological check-ups can also help detect fibroids early before they cause major symptoms.

Outlook / Prognosis

Most fibroids are benign and do not pose serious health risks. Many people never experience symptoms and may not require any treatment. For those who do experience symptoms, a wide range of treatment options are available to help manage them effectively.

Fibroids do not typically interfere with fertility, though certain types can make conception or pregnancy more difficult. With proper treatment, most women are able to maintain normal reproductive and daily function.

Living With

Can uterine fibroids come back after treatment?

Yes. Although treatment can reduce or eliminate existing fibroids, new fibroids can develop later—especially in women who are still menstruating. Hormonal therapies may suppress fibroid growth, but once treatment stops, fibroids may return.

When should I see a doctor?

You may consider speaking with a doctor if you:

  • Notice changes in menstrual bleeding
  • Feel pressure or fullness in the pelvis or abdomen
  • Have changes in urinary or bowel habits
  • Have concerns about reproductive health or a family history of fibroids

Frequently Asked Questions (FAQs)

No, fibroids are almost always benign. In very rare cases, a cancerous tumour known as a leiomyosarcoma can develop, but this is uncommon.

Some fibroids—especially those inside the uterine cavity—can interfere with implantation or increase the risk of miscarriage or complications during pregnancy. However, many women with fibroids conceive and have healthy pregnancies.

Not necessarily. Many fibroids can be managed with medication or minimally invasive procedures. Surgery is generally reserved for severe or persistent symptoms.

Fibroids do not disappear without treatment, but they may shrink after menopause when hormone levels drop.

If you are looking for more information or support in the UK, the following organisations offer helpful guidance:

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