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Erectile Dysfunction (Impotence)

Erectile dysfunction (ED), also known as impotence or impotency, is a form of penile condition affecting the ability to achieve or sustain an erection firm enough for intercourse.

Emotions play a significant role in achieving and maintaining an erection, and being relaxed, confident, and sexually aroused is very important. However, problems with erection are sometimes normal and may arise due to feelings of anxiety, nervousness, frustration, or fatigue. In addition, alcohol consumption, substance use, underlying health conditions, certain medicines, or cancer treatments might contribute to erection issues.

If you’re experiencing trouble achieving or maintaining an erection, it’s advisable to consult a healthcare professional for further evaluation. In most cases, ED could be an early sign of an underlying health issue, such as heart disease. Therefore, you should talk to a doctor if you develop any problem with erection.

Types of Erectile Dysfunction

ED is classified into different categories such as:

  • Vascular ED: This is the most common form of ED and occurs when blood flow to the penis is impaired. It may be due to issues with the blood vessels that supply the penile tissues or the valves that hold blood in the penis to maintain an erection.
  • Neurogenic ED: This arises from nerve-related issues that disrupt the signals in the brain from travelling to the penis to achieve an erection. Causes include trauma, radiation therapy, pelvic surgery, or neurological disorders such as strokes, multiple sclerosis (MS) and spinal stenosis.
  • Hormonal ED: This occurs because of testosterone deficiency. In some cases, hormonal ED can be caused by thyroid disorders.
  • Psychogenic ED: This results from psychological problems affecting one’s thoughts, emotions, or behaviors.

Erectile dysfunction is a known sexual health concern among men and persons assigned male at birth (AMAB). It’s estimated that over 50% of males aged between 40 and 70 experience ED. However, the actual percentage could be higher, as many individuals avoid seeking medical assistance because of embarrassment.

Symptoms

Symptoms of ED can occur in various ways, including:

  • Occasionally, being able to achieve an erection before sexual activity.
  • Achieving an erection before sex but being unable to sustain it during intercourse.
  • A total inability to achieve an erection.
  • Requiring excessive stimulation to achieve or sustain an erection.
Causes

Many factors can lead to erectile dysfunction, including health conditions affecting:

  • Circulatory system: The circulatory system comprises blood vessels transporting blood all over the body. To achieve and maintain an erection, the penis requires sufficient blood supply. In addition, the penis relies on a number of valves to shut once blood fills. However, these valves may sometimes stop functioning as they normally should.
  • Nervous system: The nervous system, such as the spinal cord, brain, and nerves, plays a key role in transmitting electric signals that enables movements and feeling in the body, including the penis.
  • Endocrine system: The endocrine system consists of the glands producing and releasing hormones that instruct the body to carry out particular functions. The testosterone might be essential for vasodilation or opening up of the blood vessels that facilitate blood movement to the penis.

Other factors that may contribute to ED include:

Medical conditions

  • Atherosclerosis
  • Chronic kidney disorder
  • Diabetes and diabetes-related neuropathy
  • Epilepsy
  • Hyperlipidemia (high cholesterol)
  • Hypertension (high blood pressure)
  • Peyronie’s disease
  • Stroke
  • Testosterone deficiency (low testosterone)
  • Vascular diseases

Injuries/Trauma

Injuries or trauma to the penis and the adjacent regions could also lead to ED. These include:

  • Penile fractures
  • Injuries to the bladder, pelvic bones (sacrum, hip bones, and tailbone), prostate, or spinal cord
  • Pelvic surgeries, such as colon, prostate, or bladder cancer procedures
  • Radiation therapy

Medications

Most prescription drugs list ED as a possible side effect. The most common medications include:

  • Antidepressants
  • Anxiolytics (anti-anxiety drugs)
  • Blood pressure medications
  • Diuretics
  • Antihistamines
  • Chemotherapy drugs
  • Antiseizure medications
  • Parkinson’s disease drugs
  • Prostate cancer medicines
  • Antiarrhythmic
  • Sedatives
  • Muscle relaxers

Substance use

Potentially addictive substances can lead to ED. Examples are:

  • Alcohol
  • Cocaine
  • Marijuana
  • Nicotine
  • Opioids
  • Amphetamines
  • Methadone
  • Barbiturates

Apart from affecting and suppressing the central nervous system, these substances might also result in blood vessel damage that could cause permanent ED.

Psychological and emotional problems

  • Depression
  • Stress
  • Anxiety
  • Genophobia (fear of intimacy or sexual activity)
  • Low self-esteem

Risk Factors

Your risk of developing erectile dysfunction is higher if you:

  • Are 40 years and above
  • Have diabetes
  • Have a BMI (body mass index) of more than 25
  • Are depressed
  • Smoke
  • Are physically inactive

Diagnosis

Your doctor can diagnose erectile dysfunction and examine the underlying cause by performing a physical examination and reviewing your medical history. You will also be asked some questions regarding your personal and sex history. While discussing these topics might feel awkward, being open and honest helps the provider determine the cause more quickly.

Common questions you may be asked are:

  • Are you using any medications at the moment, like prescription and non-prescription drugs, herbal or dietary supplements, or recreational drugs?
  • Have you ever been diagnosed with anxiety or depression?
  • Do you frequently feel stressed?
  • Are you undergoing any relationship challenges?
  • How frequently are you able to achieve erections?
  • How firm are your erections?
  • How long can you sustain an erection?
  • Do you lose your erection due to premature ejaculation?
  • When did you first notice symptoms of ED?
  • What happened when you first experienced ED symptoms?
  • Do you get erections at night or in the morning?
  • What sex positions do you usually engage in?

Your healthcare provider might also want to speak with your sexual partner, as they may provide more insights into the possible causes. Tests may also be ordered to detect and determine the underlying reason for your erectile dysfunction.

ED diagnostic tests

The type of tests ordered depends on the suspected cause of your ED. In most cases, these may include:

Before proceeding with any test, the doctor will explain the process and address any concerns. You can always choose not to undergo the test if you feel uncomfortable.

Treatment and Management

The most effective treatment for ED depends on its underlying cause. Your doctor can guide you in choosing the best approach.

Common treatment options involve:

Cardiovascular exercise

Engaging in vigorous cardiovascular workouts for about 45 minutes thrice a week can help reverse mild cases of ED. Examples of these exercises are brisk walking, swimming, jogging, cycling, or jumping rope.

Quit smoking

For those with mild erectile dysfunction, quitting smoking may result in significant improvement after some months.

Oral medications

Drugs like sildenafil (Viagra®), tadalafil (Cialis®), vardenafil (Levitra®), and avanafil (Stendra®) boost blood supply to the penis and are usually effective after an hour.

Penile low-intensity focused shockwave therapy (LiSWT):

This uses sound waves to increase blood flow. Results may be observed within two months.

Injectable medications

Medications such as papaverine (Papacon®), alprostadil (Caverject®), and phentolamine (Regitine®) or even a combination of many drugs are injected directly into the penis to trigger an erection. Results will be noticed within 10 minutes.

Testosterone replacement therapy

Available in the form of gels, patches, injections, or pellets, this treatment starts working within 4 weeks.

Vacuum constriction devices

These penis pumps are effective, and the results are almost immediate.

Penile implant

This surgical procedure involves placing a device inside the penis to achieve firmness. Implants do not affect feeling, urination, or orgasm.

Consulting a sex therapist

In most cases, ED does not resolve on its own without treatment or lifestyle changes.

Prevention

Some lifestyle changes may reduce the possibility of developing ED. These include:

  • Limiting cholesterol
  • Engaging in regular physical activity, particularly cardiovascular exercises such as running, cycling or jogging.
  • Maintaining a healthy weight
  • Getting quality sleep.
  • Eating a nutritious diet rich in fruits, whole grains, and vegetables and low in saturated fats.
  • Quitting smoking.
  • Limiting or quitting alcohol.

Outlook / Prognosis

The erectile dysfunction outlook is positive, as it’s a highly treatable problem. While some causes may not be curable, several effective treatment options are available to help achieve and maintain an erection suitable for sexual activity.

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