Private Myotonic Dystrophy Type 2 (PROMM) - ZNF9 repeat PCR Test London
Myotonic Dystrophy Type 2 (PROMM) - ZNF9 repeat PCR for accurate detection of infections and guide treatment.
Myotonic Dystrophy Type 2 (PROMM) - ZNF9 repeat PCR
Test fee £560 + £50 phlebotomy fee (per visit)
- Results in 6 weeks"
- UKAS accredited laboratory
- Professional phlebotomy service
- Confidential results portal
Or call 020 7183 2362
Pay at clinic on the day of your appointment
Myotonic Dystrophy Type 2 (PROMM) – ZNF9 Repeat Analysis in London
Myotonic Dystrophy Type 2 (DM2/PROMM) ZNF9 (CNBP) repeat analysis is available at South Kensington Medical and Dental, our CQC-registered clinic in South Kensington, London SW7. This test is priced at £560. A £50 phlebotomy fee applies per visit for blood collection. It requires a venous blood sample, and results are typically available within 6 weeks. A referral from a clinical neurologist or clinical geneticist is required before this test can be ordered.
Myotonic Dystrophy Type 2 (DM2), also known as Proximal Myotonic Myopathy (PROMM), is caused by an expansion of CCTG tetranucleotide repeats in the CNBP (ZNF9) gene on chromosome 3q. This PCR-based test detects the pathogenic repeat expansion. DM2 is generally milder than DM1 and does not show significant anticipation.
Who Should Consider DM2 ZNF9 Repeat Testing?
Individuals with proximal muscle weakness, myotonia, muscle pain, cataracts, or cardiac conduction abnormalities where DM1 testing has been negative. Those with a family history of DM2 seeking predictive testing. DM2 typically presents later in life (third to sixth decade) with milder symptoms than DM1.
Normal alleles have up to 26 CCTG repeats. Pathogenic expansions range from approximately 75 to over 11,000 repeats. Unlike DM1, there is no congenital form of DM2 and the condition does not show significant anticipation. Genetic counselling is recommended to discuss inheritance and implications for family members.
A trained nurse collects the blood sample by standard venepuncture at our clinic on Old Brompton Road, directly opposite South Kensington tube station (Piccadilly, Circle, and District lines). A referral from a clinical neurologist or clinical geneticist is required — please call 020 7183 2362 to arrange.
Infection Detection
Accurate infection testing helps diagnose and guide effective treatment.
- Active symptoms
- Exposure concerns
- Travel health
- Pre-procedure screening
- Contact tracing
- Recovery monitoring
How It Works
Book Online
Choose a convenient date and time
Visit Our Clinic
20 Old Brompton Road, South Kensington
Quick Blood Draw
Professional phlebotomy, 5 minutes
Get Results
Results in 6 weeks"
Frequently Asked Questions
Common questions about this blood test
Visit Our London Clinic
Central London location with excellent transport links
Address
South Kensington Medical & Dental
20 Old Brompton Road
South Kensington
London SW7 3DL
Getting Here
- 2-minute walk from South Kensington tube
- Circle, District & Piccadilly lines
Opening Hours
- Monday, Wednesday9am - 6pm
- Tuesday, Thursday9am - 8pm
- Friday8am - 5pm
- Saturday10am - 4pm
- Sunday10am - 4pm
Contact
Ready to Book Your Test?
No GP referral needed. Book online and get tested at our South Kensington clinic. Results within 6 weeks".
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Meet Our Medical Team
Our experienced medical team is fully qualified and registered with the GMC and NMC, delivering safe, high-quality care in line with the highest professional standards.
Because our patients deserve nothing less.
Registered. Regulated. Trusted.
At South Kensington Medical & Dental, we are fully registered with the Care Quality Commission (CQC) and our clinicians are registered with the relevant UK regulatory bodies, including the GDC and GMC. Our dentists, dental nurses and medical professionals deliver care that meets the highest clinical, safety and ethical standards, because our patients deserve nothing less.
